BDBM50220829 CHEMBL307089

SMILES: NC(=N)N1CCC(C[C@@H]2[C@H](N(C(=O)Nc3ccccc3)C2=O)C(O)=O)CC1

InChI Key: InChIKey=NTACNIGASKYVDY-KGLIPLIRSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50220829   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tryptase (Homo sapiens (Human))	BDBM50220829 (CHEMBL307089) Show SMILES NC(=N)N1CCC(C[C@@H]2[C@H](N(C(=O)Nc3ccccc3)C2=O)C(O)=O)CC1 Show InChI InChI=1S/C18H23N5O4/c19-17(20)22-8-6-11(7-9-22)10-13-14(16(25)26)23(15(13)24)18(27)21-12-4-2-1-3-5-12/h1-5,11,13-14H,6-10H2,(H3,19,20)(H,21,27)(H,25,26)/t13-,14+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	515	n/a	n/a	n/a	n/a	n/a	n/a
The Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity of compound against human tryptase was determined				Bioorg Med Chem Lett 14: 2227-31 (2004) Article DOI: 10.1016/j.bmcl.2004.02.011 BindingDB Entry DOI: 10.7270/Q2GM86Q3
					More data for this Ligand-Target Pair