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BDBM50221168 CHEMBL247602::N-(4-(8a-benzyl-6-oxo-3,4,6,7,8,8a-hexahydroisoquinolin-2(1H)-ylsulfonyl)phenyl)acetamide

SMILES: CC(=O)Nc1ccc(cc1)S(=O)(=O)N1CCC2=CC(=O)CCC2(Cc2ccccc2)C1

InChI Key: InChIKey=UPKLLTWXWRQKFC-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50221168   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glucocorticoid receptor


(Homo sapiens (Human))		BDBM50221168
PNG
(CHEMBL247602 | N-(4-(8a-benzyl-6-oxo-3,4,6,7,8,8a-...)
Show SMILES CC(=O)Nc1ccc(cc1)S(=O)(=O)N1CCC2=CC(=O)CCC2(Cc2ccccc2)C1 |t:17|
Show InChI InChI=1S/C24H26N2O4S/c1-18(27)25-21-7-9-23(10-8-21)31(29,30)26-14-12-20-15-22(28)11-13-24(20,17-26)16-19-5-3-2-4-6-19/h2-10,15H,11-14,16-17H2,1H3,(H,25,27)
PDB

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Similars
Article
PubMed
 750n/an/an/an/an/an/an/an/a



Corcept Therapeutics

Curated by ChEMBL


Assay Description
Displacement of [3H]dexamethasone from human glucocorticoid receptor expressed in recombinant baculovirus

Bioorg Med Chem Lett 17: 5704-8 (2007)


Article DOI: 10.1016/j.bmcl.2007.07.055
BindingDB Entry DOI: 10.7270/Q2FX7B8B
More data for this
Ligand-Target Pair