BDBM50221179 CHEMBL398668::N-(4-((2-(4-tert-butylphenylsulfonyl)-6-oxo-1,2,3,4,6,7,8,8a-octahydroisoquinolin-8a-yl)methyl)phenyl)acetamide

SMILES: CC(=O)Nc1ccc(CC23CCC(=O)C=C2CCN(C3)S(=O)(=O)c2ccc(cc2)C(C)(C)C)cc1

InChI Key: InChIKey=SLHBMTBEWGNQIF-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50221179   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50221179 (CHEMBL398668 | N-(4-((2-(4-tert-butylphenylsulfony...) Show SMILES CC(=O)Nc1ccc(CC23CCC(=O)C=C2CCN(C3)S(=O)(=O)c2ccc(cc2)C(C)(C)C)cc1 |c:14| Show InChI InChI=1S/C28H34N2O4S/c1-20(31)29-24-9-5-21(6-10-24)18-28-15-13-25(32)17-23(28)14-16-30(19-28)35(33,34)26-11-7-22(8-12-26)27(2,3)4/h5-12,17H,13-16,18-19H2,1-4H3,(H,29,31)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	56	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Displacement of [3H]dexamethasone from human glucocorticoid receptor expressed in recombinant baculovirus				Bioorg Med Chem Lett 17: 5704-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.055 BindingDB Entry DOI: 10.7270/Q2FX7B8B
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50221179 (CHEMBL398668 | N-(4-((2-(4-tert-butylphenylsulfony...) Show SMILES CC(=O)Nc1ccc(CC23CCC(=O)C=C2CCN(C3)S(=O)(=O)c2ccc(cc2)C(C)(C)C)cc1 |c:14| Show InChI InChI=1S/C28H34N2O4S/c1-20(31)29-24-9-5-21(6-10-24)18-28-15-13-25(32)17-23(28)14-16-30(19-28)35(33,34)26-11-7-22(8-12-26)27(2,3)4/h5-12,17H,13-16,18-19H2,1-4H3,(H,29,31)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Corcept Therapeutics Curated by ChEMBL					Assay Description Antagonist activity at human glucocorticoid receptor in SW1353 cells assessed as inhibition of dexamethasone-induced luciferase expression by MMTV5 r...				Bioorg Med Chem Lett 17: 5704-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.055 BindingDB Entry DOI: 10.7270/Q2FX7B8B
					More data for this Ligand-Target Pair