BDBM50221297 CHEMBL239393::N-butyloxycarbonyl-3-[4-(N,N-dimethylcarbamoylmethyl)phenyl]-5-iso-butylthiophene-2-sulfonamide::butyl 3-(4-(2-(dimethylamino)-2-oxoethyl)phenyl)-5-isobutylthiophen-2-ylsulfonylcarbamate
SMILES: CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(CC(=O)N(C)C)cc1
InChI Key: InChIKey=MJVHOJCMTONSPL-UHFFFAOYSA-N
Data: 3 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Type-1 angiotensin II receptor (Sus scrofa) | BDBM50221297 (CHEMBL239393 | N-butyloxycarbonyl-3-[4-(N,N-dimeth...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University Curated by ChEMBL | Assay Description Displacement of [125]Ang2 from AT2 receptor in pig uterus membrane | Bioorg Med Chem 16: 6841-9 (2008) Article DOI: 10.1016/j.bmc.2008.05.066 BindingDB Entry DOI: 10.7270/Q22F7N7C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
AGTR1 (RAT) | BDBM50221297 (CHEMBL239393 | N-butyloxycarbonyl-3-[4-(N,N-dimeth...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University Curated by ChEMBL | Assay Description Displacement of [125I]Ang 2 from AT1 receptor in rat liver membranes | Bioorg Med Chem 15: 7166-83 (2007) Article DOI: 10.1016/j.bmc.2007.07.026 BindingDB Entry DOI: 10.7270/Q2DJ5FBM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
AGTR1 (RAT) | BDBM50221297 (CHEMBL239393 | N-butyloxycarbonyl-3-[4-(N,N-dimeth...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University Curated by ChEMBL | Assay Description Displacement of [125]Ang2 from AT1 receptor in rat liver membrane | Bioorg Med Chem 16: 6841-9 (2008) Article DOI: 10.1016/j.bmc.2008.05.066 BindingDB Entry DOI: 10.7270/Q22F7N7C | |||||||||||
More data for this Ligand-Target Pair |