BDBM50221759 2-(4-hydroxybenzyl)-6-hydroxy-4H-pyrido[1,2-a]pyrimidin-4-one::CHEMBL242419

SMILES: Oc1ccc(Cc2cc(=O)n3c(O)cccc3n2)cc1

InChI Key: InChIKey=MCYZKHPHZKNHJC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50221759   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aldose reductase (Rattus norvegicus)	BDBM50221759 (2-(4-hydroxybenzyl)-6-hydroxy-4H-pyrido[1,2-a]pyri...) Show SMILES Oc1ccc(Cc2cc(=O)n3c(O)cccc3n2)cc1 Show InChI InChI=1S/C15H12N2O3/c18-12-6-4-10(5-7-12)8-11-9-15(20)17-13(16-11)2-1-3-14(17)19/h1-7,9,18-19H,8H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Inhibition of ALR1 in Sprague-Dawley Albino rat kidney				J Med Chem 50: 4917-27 (2007) Article DOI: 10.1021/jm070398a BindingDB Entry DOI: 10.7270/Q2TM79TD
					More data for this Ligand-Target Pair