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BDBM50221888 CHEMBL390227::trimethyl-(4-quinolin-6-yl-but-3-ynyl)-ammonium iodide

SMILES: C[N+](C)(C)CCC#Cc1ccc2ncccc2c1

InChI Key: InChIKey=MCYJBKDFWKMBLZ-UHFFFAOYSA-N

Data: 2 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50221888
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Neuronal acetylcholine receptor (Rattus norvegicus (Rat))	BDBM50221888 (CHEMBL390227 \| trimethyl-(4-quinolin-6-yl-but-3-yn...) Show SMILES C[N+](C)(C)CCC#Cc1ccc2ncccc2c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	142	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Florence Curated by ChEMBL					Assay Description Displacement of [3H]alpha-bungarotoxin from alpha7 nAChR in rat cerebral cortex				J Med Chem 50: 4993-5002 (2007) Article DOI: 10.1021/jm070325r BindingDB Entry DOI: 10.7270/Q2FF3S34
University of Florence Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit (Rattus norvegicus (Rat))	BDBM50221888 (CHEMBL390227 \| trimethyl-(4-quinolin-6-yl-but-3-yn...) Show SMILES C[N+](C)(C)CCC#Cc1ccc2ncccc2c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	6.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Florence Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cerebral cortex				J Med Chem 50: 4993-5002 (2007) Article DOI: 10.1021/jm070325r BindingDB Entry DOI: 10.7270/Q2FF3S34
University of Florence Curated by ChEMBL					More data for this Ligand-Target Pair