BDBM50222049 CHEMBL90150

SMILES: Cc1c(NC2=NCCN2)cccc1-c1cccc(c1)C(F)(F)F

InChI Key: InChIKey=YEXKVPUWSQVAIA-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50222049   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serotonin (5-HT) receptor (Rattus norvegicus (rat))	BDBM50222049 (CHEMBL90150) Show SMILES Cc1c(NC2=NCCN2)cccc1-c1cccc(c1)C(F)(F)F |t:4| Show InChI InChI=1S/C17H16F3N3/c1-11-14(12-4-2-5-13(10-12)17(18,19)20)6-3-7-15(11)23-16-21-8-9-22-16/h2-7,10H,8-9H2,1H3,(H2,21,22,23)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	46	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of [3H]-5-CT binding to 5-hydroxytryptamine 7 receptor of rat cortical membranes				Bioorg Med Chem Lett 13: 269-71 (2003) BindingDB Entry DOI: 10.7270/Q2GQ7108
					More data for this Ligand-Target Pair
Adrenergic receptor alpha-2 (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50222049 (CHEMBL90150) Show SMILES Cc1c(NC2=NCCN2)cccc1-c1cccc(c1)C(F)(F)F |t:4| Show InChI InChI=1S/C17H16F3N3/c1-11-14(12-4-2-5-13(10-12)17(18,19)20)6-3-7-15(11)23-16-21-8-9-22-16/h2-7,10H,8-9H2,1H3,(H2,21,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	79	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Affinity for Alpha-2 adrenergic receptor of rat cortical membranes				Bioorg Med Chem Lett 13: 269-71 (2003) BindingDB Entry DOI: 10.7270/Q2GQ7108
					More data for this Ligand-Target Pair
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50222049 (CHEMBL90150) Show SMILES Cc1c(NC2=NCCN2)cccc1-c1cccc(c1)C(F)(F)F |t:4| Show InChI InChI=1S/C17H16F3N3/c1-11-14(12-4-2-5-13(10-12)17(18,19)20)6-3-7-15(11)23-16-21-8-9-22-16/h2-7,10H,8-9H2,1H3,(H2,21,22,23)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	257	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Affinity for Alpha-1 adrenergic receptor of rat cortical membranes				Bioorg Med Chem Lett 13: 269-71 (2003) BindingDB Entry DOI: 10.7270/Q2GQ7108
					More data for this Ligand-Target Pair