BDBM50222053 CHEMBL90752
SMILES: Cc1cccc(c1)-c1cccc(NC2=NCCN2)c1C
InChI Key: InChIKey=NKNBGEKNGQTKAD-UHFFFAOYSA-N
Data: 3 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Adrenergic receptor alpha-2 (RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50222053 (CHEMBL90752) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Affinity for Alpha-2 adrenergic receptor of rat cortical membranes | Bioorg Med Chem Lett 13: 269-71 (2003) BindingDB Entry DOI: 10.7270/Q2GQ7108 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin (5-HT) receptor (Rattus norvegicus (rat)) | BDBM50222053 (CHEMBL90752) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 21 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of [3H]-5-CT binding to 5-hydroxytryptamine 7 receptor of rat cortical membranes | Bioorg Med Chem Lett 13: 269-71 (2003) BindingDB Entry DOI: 10.7270/Q2GQ7108 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50222053 (CHEMBL90752) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 166 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Affinity for Alpha-1 adrenergic receptor of rat cortical membranes | Bioorg Med Chem Lett 13: 269-71 (2003) BindingDB Entry DOI: 10.7270/Q2GQ7108 | |||||||||||
More data for this Ligand-Target Pair |