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SMILES: CN1C(=O)N(C(CCc2ccncc2)COc2ccc(cc2)-c2cccc(c2)[N+]([O-])=O)C(=O)C1(C)C

InChI Key: InChIKey=OOFPNOMLOCGMBW-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50222399   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
P2X purinoceptor 7


(Homo sapiens (Human))		BDBM50222399
PNG
(CHEMBL337016)
Show SMILES CN1C(=O)N(C(CCc2ccncc2)COc2ccc(cc2)-c2cccc(c2)[N+]([O-])=O)C(=O)C1(C)C
Show InChI InChI=1S/C27H28N4O5/c1-27(2)25(32)30(26(33)29(27)3)23(10-7-19-13-15-28-16-14-19)18-36-24-11-8-20(9-12-24)21-5-4-6-22(17-21)31(34)35/h4-6,8-9,11-17,23H,7,10,18H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a<1.00E+4n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
In vitro antagonism of P2X 7 receptor in THP-1 (human pre-monocytic) cells.

Bioorg Med Chem Lett 13: 4043-6 (2003)


BindingDB Entry DOI: 10.7270/Q2930VCQ
More data for this
Ligand-Target Pair