BDBM50222506 CHEMBL400102::N-(4-(4-methylpiperazin-1-yl)phenyl)-2-(pyridin-4-ylmethylamino)nicotinamide

SMILES: CN1CCN(CC1)c1ccc(NC(=O)c2cccnc2NCc2ccncc2)cc1

InChI Key: InChIKey=BCWZQULSEUVUOY-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50222506   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50222506 (CHEMBL400102 | N-(4-(4-methylpiperazin-1-yl)phenyl...) Show SMILES CN1CCN(CC1)c1ccc(NC(=O)c2cccnc2NCc2ccncc2)cc1 Show InChI InChI=1S/C23H26N6O/c1-28-13-15-29(16-14-28)20-6-4-19(5-7-20)27-23(30)21-3-2-10-25-22(21)26-17-18-8-11-24-12-9-18/h2-12H,13-17H2,1H3,(H,25,26)(H,27,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>6.66E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Curated by ChEMBL					Assay Description Inhibition of phosphorylated-Kdr after 30 mins				Bioorg Med Chem Lett 17: 6003-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.077 BindingDB Entry DOI: 10.7270/Q27P8Z3N
					More data for this Ligand-Target Pair