BDBM50222514 CHEMBL249599::N-(3-(1-hydroxyethyl)phenyl)-2-(pyridin-4-ylmethylamino)nicotinamide

SMILES: CC(O)c1cccc(NC(=O)c2cccnc2NCc2ccncc2)c1

InChI Key: InChIKey=VLGRTBMJNUAXTL-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50222514   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50222514 (CHEMBL249599 | N-(3-(1-hydroxyethyl)phenyl)-2-(pyr...) Show SMILES CC(O)c1cccc(NC(=O)c2cccnc2NCc2ccncc2)c1 |w:1.0| Show InChI InChI=1S/C20H20N4O2/c1-14(25)16-4-2-5-17(12-16)24-20(26)18-6-3-9-22-19(18)23-13-15-7-10-21-11-8-15/h2-12,14,25H,13H2,1H3,(H,22,23)(H,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>6.66E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Curated by ChEMBL					Assay Description Inhibition of phosphorylated-Kdr after 30 mins				Bioorg Med Chem Lett 17: 6003-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.077 BindingDB Entry DOI: 10.7270/Q27P8Z3N
					More data for this Ligand-Target Pair