BDBM50222623 CHEMBL356994
SMILES: CC1(C)CC(CC(C)(C)N1)Nc1cc2N(C(=O)NCc2c(c1)-c1ccccc1Cl)c1c(Cl)cccc1Cl
InChI Key: InChIKey=WLSRUNCRTNITTJ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50222623 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
MAP kinase p38
(Homo sapiens (Human)) | BDBM50222623
(CHEMBL356994)Show SMILES CC1(C)CC(CC(C)(C)N1)Nc1cc2N(C(=O)NCc2c(c1)-c1ccccc1Cl)c1c(Cl)cccc1Cl Show InChI InChI=1S/C29H31Cl3N4O/c1-28(2)14-18(15-29(3,4)35-28)34-17-12-20(19-8-5-6-9-22(19)30)21-16-33-27(37)36(25(21)13-17)26-23(31)10-7-11-24(26)32/h5-13,18,34-35H,14-16H2,1-4H3,(H,33,37) | PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck& Co.
Curated by ChEMBL
| Assay Description
Inhibition of p38 MAP kinase |
Bioorg Med Chem Lett 13: 467-70 (2003)
BindingDB Entry DOI: 10.7270/Q22F7QM4 |
More data for this
Ligand-Target Pair | |
MAP kinase p38
(Homo sapiens (Human)) | BDBM50222623
(CHEMBL356994)Show SMILES CC1(C)CC(CC(C)(C)N1)Nc1cc2N(C(=O)NCc2c(c1)-c1ccccc1Cl)c1c(Cl)cccc1Cl Show InChI InChI=1S/C29H31Cl3N4O/c1-28(2)14-18(15-29(3,4)35-28)34-17-12-20(19-8-5-6-9-22(19)30)21-16-33-27(37)36(25(21)13-17)26-23(31)10-7-11-24(26)32/h5-13,18,34-35H,14-16H2,1-4H3,(H,33,37) | PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck& Co.
Curated by ChEMBL
| Assay Description
Inhibition of p38 kinase related TNF-alpha release |
Bioorg Med Chem Lett 13: 467-70 (2003)
BindingDB Entry DOI: 10.7270/Q22F7QM4 |
More data for this
Ligand-Target Pair | |
Search and Browse
