BDBM50222724 CHEMBL19669

SMILES: CCc1ccc(OC(C)C(O)CNC(C)(C)C)cc1

InChI Key: InChIKey=DWGXLLQFKBFURM-UHFFFAOYSA-N

Data: 1 Kd  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50222724   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adrenergic receptor beta (Rattus norvegicus (Rat))	BDBM50222724 (CHEMBL19669) Show SMILES CCc1ccc(OC(C)C(O)CNC(C)(C)C)cc1 Show InChI InChI=1S/C16H27NO2/c1-6-13-7-9-14(10-8-13)19-12(2)15(18)11-17-16(3,4)5/h7-10,12,15,17-18H,6,11H2,1-5H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against Beta adrenergic receptor in C6-2B astrocytoma cells, using [125I]-iodohydroxybenzylpindolol-benzylpindolol([125I]-HYP)				J Med Chem 24: 1211-4 (1981) BindingDB Entry DOI: 10.7270/Q2CN7632
					More data for this Ligand-Target Pair
Beta-2 adrenergic receptor (GUINEA PIG)	BDBM50222724 (CHEMBL19669) Show SMILES CCc1ccc(OC(C)C(O)CNC(C)(C)C)cc1 Show InChI InChI=1S/C16H27NO2/c1-6-13-7-9-14(10-8-13)19-12(2)15(18)11-17-16(3,4)5/h7-10,12,15,17-18H,6,11H2,1-5H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	1.92E+3	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Blocking activity against Beta-2 adrenergic receptor in guinea pig tracheal strips				J Med Chem 24: 1211-4 (1981) BindingDB Entry DOI: 10.7270/Q2CN7632
					More data for this Ligand-Target Pair
Beta-1 adrenergic receptor (GUINEA PIG)	BDBM50222724 (CHEMBL19669) Show SMILES CCc1ccc(OC(C)C(O)CNC(C)(C)C)cc1 Show InChI InChI=1S/C16H27NO2/c1-6-13-7-9-14(10-8-13)19-12(2)15(18)11-17-16(3,4)5/h7-10,12,15,17-18H,6,11H2,1-5H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	199	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Blocking activity against Beta-1 adrenergic receptor in spontaneously beating guinea pig atrial preparations				J Med Chem 24: 1211-4 (1981) BindingDB Entry DOI: 10.7270/Q2CN7632
					More data for this Ligand-Target Pair