BDBM50223069 CHEMBL250461::N-[2-(carbamimidamidooxy)ethyl]-2-(6-chloro-3-{[2,2-difluoro-2-(4-fluoronaphthalen-1-yl)ethyl]amino}-2-fluorophenyl)acetamide

SMILES: [#7]\[#6](-[#7])=[#7]\[#8]-[#6]-[#6]-[#7]-[#6](=O)-[#6]-c1c(Cl)ccc(-[#7]-[#6]C(F)(F)c2ccc(F)c3ccccc23)c1F

InChI Key: InChIKey=LSSPSEWHOYRDFX-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50223069   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prothrombin (Homo sapiens (Human))	BDBM50223069 (CHEMBL250461 | N-[2-(carbamimidamidooxy)ethyl]-2-(...) Show SMILES [#7]\[#6](-[#7])=[#7]\[#8]-[#6]-[#6]-[#7]-[#6](=O)-[#6]-c1c(Cl)ccc(-[#7]-[#6]C(F)(F)c2ccc(F)c3ccccc23)c1F Show InChI InChI=1S/C23H22ClF4N5O2/c24-17-6-8-19(21(26)15(17)11-20(34)31-9-10-35-33-22(29)30)32-12-23(27,28)16-5-7-18(25)14-4-2-1-3-13(14)16/h1-8,32H,9-12H2,(H,31,34)(H4,29,30,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Curated by ChEMBL					Assay Description Inhibition of human thrombin after 15 mins by standard chromogenic assay				Bioorg Med Chem Lett 17: 6266-9 (2007) Article DOI: 10.1016/j.bmcl.2007.09.013 BindingDB Entry DOI: 10.7270/Q29G5MH9
					More data for this Ligand-Target Pair