BDBM50223194 CHEMBL33984

SMILES: COc1ccc(cc1)-c1cc2nc(ccc2c(NCCCN)n1)C(F)(F)F

InChI Key: InChIKey=KOFODTPSIXYGCY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50223194   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM50223194 (CHEMBL33984) Show SMILES COc1ccc(cc1)-c1cc2nc(ccc2c(NCCCN)n1)C(F)(F)F Show InChI InChI=1S/C19H19F3N4O/c1-27-13-5-3-12(4-6-13)15-11-16-14(18(26-15)24-10-2-9-23)7-8-17(25-16)19(20,21)22/h3-8,11H,2,9-10,23H2,1H3,(H,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>30	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against spleen tyrosine kinase (SYK)				Bioorg Med Chem Lett 13: 1415-8 (2003) BindingDB Entry DOI: 10.7270/Q2MC8ZCJ
					More data for this Ligand-Target Pair