BDBM50223224 CHEMBL65115

SMILES: CCOc1cc(ccc1OC)C1(CCN(CC(=O)NO)CC1)C#N

InChI Key: InChIKey=RSLMMIUFYJQNAI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50223224   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D (Homo sapiens (Human))	BDBM50223224 (CHEMBL65115) Show SMILES CCOc1cc(ccc1OC)C1(CCN(CC(=O)NO)CC1)C#N Show InChI InChI=1S/C17H23N3O4/c1-3-24-15-10-13(4-5-14(15)23-2)17(12-18)6-8-20(9-7-17)11-16(21)19-22/h4-5,10,22H,3,6-9,11H2,1-2H3,(H,19,21)	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.520	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Inhibition of phosphodiesterase 4 (PDE4) prepared from human U937 cells				Bioorg Med Chem Lett 14: 207-10 (2004) BindingDB Entry DOI: 10.7270/Q21G0PFV
					More data for this Ligand-Target Pair