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SMILES: COc1ccc(cc1OC1CCCC1)C1(CCN(CC(=O)NO)CC1)C#N

InChI Key: InChIKey=VXYDHPDQMSVQCU-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50223272   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D


(Homo sapiens (Human))		BDBM50223272
PNG
(CHEMBL67668)
Show SMILES COc1ccc(cc1OC1CCCC1)C1(CCN(CC(=O)NO)CC1)C#N
Show InChI InChI=1S/C20H27N3O4/c1-26-17-7-6-15(12-18(17)27-16-4-2-3-5-16)20(14-21)8-10-23(11-9-20)13-19(24)22-25/h6-7,12,16,25H,2-5,8-11,13H2,1H3,(H,22,24)
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n/an/a 0.0800n/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Inhibition of phosphodiesterase 4 (PDE4) prepared from human U937 cells

Bioorg Med Chem Lett 14: 207-10 (2004)


BindingDB Entry DOI: 10.7270/Q21G0PFV
More data for this
Ligand-Target Pair