BDBM50223377 1-adamantan-1-yl-3-{4-[2-(2-ethoxyethoxy)ethoxy]cyclohexyl}urea::CHEMBL244068

SMILES: CCOCCOCCOC1CCC(CC1)NC(=O)NC12CC3CC(CC(C3)C1)C2

InChI Key: InChIKey=QFZFOAIFCJUCDP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50223377   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
EBifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50223377 (1-adamantan-1-yl-3-{4-[2-(2-ethoxyethoxy)ethoxy]cy...) Show SMILES CCOCCOCCOC1CCC(CC1)NC(=O)NC12CC3CC(CC(C3)C1)C2 |TLB:18:19:22.21.26:24,THB:20:21:24:28.19.27,20:19:22.21.26:24,27:19:22:26.25.24,27:25:22:28.20.19,18:19:22:26.25.24,(31.61,-36.54,;30.89,-37.9,;29.35,-37.96,;28.63,-39.32,;27.09,-39.37,;26.37,-40.73,;24.83,-40.79,;24.11,-42.15,;22.57,-42.21,;21.75,-40.9,;20.21,-40.95,;19.4,-39.66,;20.12,-38.3,;21.66,-38.23,;22.47,-39.54,;19.3,-37,;17.76,-37.06,;16.94,-35.76,;17.04,-38.43,;15.51,-38.49,;14.49,-39.76,;13.08,-39.2,;11.59,-39.62,;12.78,-38.35,;12.77,-36.86,;14.12,-36.38,;13.08,-37.61,;15.52,-36.96,;14.11,-38.83,)| Show InChI InChI=1S/C23H40N2O4/c1-2-27-7-8-28-9-10-29-21-5-3-20(4-6-21)24-22(26)25-23-14-17-11-18(15-23)13-19(12-17)16-23/h17-21H,2-16H2,1H3,(H2,24,25,26)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Department of Entomology and University of California Davis Cancer Center Curated by ChEMBL					Assay Description Inhibition of human recombinant soluble epoxide hydrolase by fluorescent based assay				J Med Chem 50: 5217-26 (2007) Article DOI: 10.1021/jm070705c BindingDB Entry DOI: 10.7270/Q24T6J3C
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