BDBM50223426 CHEBI:10304::Corbadrine::LEVONORDEFRIN::Levonordefrin::Neo-Cobefrin::Nordefrin

SMILES: [H][C@@](C)(N)[C@]([H])(O)c1ccc(O)c(O)c1

InChI Key: InChIKey=GEFQWZLICWMTKF-CDUCUWFYSA-N

Data: 6 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50223426   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adrenergic receptor alpha-2 (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50223426 (CHEBI:10304 | Corbadrine | LEVONORDEFRIN | Levonor...) Show SMILES [H][C@@](C)(N)[C@]([H])(O)c1ccc(O)c(O)c1 |r| Show InChI InChI=1S/C9H13NO3/c1-5(10)9(13)6-2-3-7(11)8(12)4-6/h2-5,9,11-13H,10H2,1H3/t5-,9-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	PubMed	7.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]clonidine from Alpha-2 adrenergic receptor of rat brain membranes				J Med Chem 25: 1389-401 (1982) BindingDB Entry DOI: 10.7270/Q2251MCQ
					More data for this Ligand-Target Pair
Adrenergic receptor alpha-2 (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50223426 (CHEBI:10304 | Corbadrine | LEVONORDEFRIN | Levonor...) Show SMILES [H][C@@](C)(N)[C@]([H])(O)c1ccc(O)c(O)c1 |r| Show InChI InChI=1S/C9H13NO3/c1-5(10)9(13)6-2-3-7(11)8(12)4-6/h2-5,9,11-13H,10H2,1H3/t5-,9-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	205	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ohio State University Curated by ChEMBL					Assay Description Alpha-2 adrenergic receptor binding affinity was tested against membrane preparations of rat brain.				J Med Chem 39: 3001-13 (1996) Article DOI: 10.1021/jm9506074 BindingDB Entry DOI: 10.7270/Q2BV7KBH
					More data for this Ligand-Target Pair
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50223426 (CHEBI:10304 | Corbadrine | LEVONORDEFRIN | Levonor...) Show SMILES [H][C@@](C)(N)[C@]([H])(O)c1ccc(O)c(O)c1 |r| Show InChI InChI=1S/C9H13NO3/c1-5(10)9(13)6-2-3-7(11)8(12)4-6/h2-5,9,11-13H,10H2,1H3/t5-,9-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	PubMed	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for inhibition of [3H]prazosin binding to Alpha-1 adrenergic receptor in rat forebrain homogenate.				J Med Chem 24: 1261-3 (1981) BindingDB Entry DOI: 10.7270/Q2445PPC
					More data for this Ligand-Target Pair
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50223426 (CHEBI:10304 | Corbadrine | LEVONORDEFRIN | Levonor...) Show SMILES [H][C@@](C)(N)[C@]([H])(O)c1ccc(O)c(O)c1 |r| Show InChI InChI=1S/C9H13NO3/c1-5(10)9(13)6-2-3-7(11)8(12)4-6/h2-5,9,11-13H,10H2,1H3/t5-,9-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	PubMed	7.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for inhibition of [3H]prazosin binding to Alpha-1 adrenergic receptor in rat forebrain homogenate.				J Med Chem 24: 1261-3 (1981) BindingDB Entry DOI: 10.7270/Q2445PPC
					More data for this Ligand-Target Pair
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50223426 (CHEBI:10304 | Corbadrine | LEVONORDEFRIN | Levonor...) Show SMILES [H][C@@](C)(N)[C@]([H])(O)c1ccc(O)c(O)c1 |r| Show InChI InChI=1S/C9H13NO3/c1-5(10)9(13)6-2-3-7(11)8(12)4-6/h2-5,9,11-13H,10H2,1H3/t5-,9-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	9.22E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ohio State University Curated by ChEMBL					Assay Description Alpha-1 adrenergic receptor binding affinity in rat brain membranes				J Med Chem 39: 3001-13 (1996) Article DOI: 10.1021/jm9506074 BindingDB Entry DOI: 10.7270/Q2BV7KBH
					More data for this Ligand-Target Pair
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50223426 (CHEBI:10304 | Corbadrine | LEVONORDEFRIN | Levonor...) Show SMILES [H][C@@](C)(N)[C@]([H])(O)c1ccc(O)c(O)c1 |r| Show InChI InChI=1S/C9H13NO3/c1-5(10)9(13)6-2-3-7(11)8(12)4-6/h2-5,9,11-13H,10H2,1H3/t5-,9-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	PubMed	2.32E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for inhibition of [3H]prazosin binding to Alpha-1 adrenergic receptor in rat forebrain homogenate.				J Med Chem 24: 1261-3 (1981) BindingDB Entry DOI: 10.7270/Q2445PPC
					More data for this Ligand-Target Pair