BDBM50223499 CHEMBL25701

SMILES: COc1ccc(Cc2nccn2Cc2ccc(NC(=O)c3ccccc3C(O)=O)cc2)cc1

InChI Key: InChIKey=MXHWGGVFTAYENC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50223499   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin II receptor (RAT)	BDBM50223499 (CHEMBL25701) Show SMILES COc1ccc(Cc2nccn2Cc2ccc(NC(=O)c3ccccc3C(O)=O)cc2)cc1 Show InChI InChI=1S/C26H23N3O4/c1-33-21-12-8-18(9-13-21)16-24-27-14-15-29(24)17-19-6-10-20(11-7-19)28-25(30)22-4-2-3-5-23(22)26(31)32/h2-15H,16-17H2,1H3,(H,28,30)(H,31,32)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
E. I. du Pont de Nemours& Company, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration that gave 50 percent displacement of specific binding of [3H]AII (2 nM) to Angiotensin ll receptor				J Med Chem 33: 1312-29 (1990) BindingDB Entry DOI: 10.7270/Q2TM7DCT
					More data for this Ligand-Target Pair