BDBM50223570 3-bromo-5-(2-fluorophenyl)-N-phenylpyrazolo[1,5-a]pyrimidin-7-amine::CHEMBL400239

SMILES: Fc1ccccc1-c1cc(Nc2ccccc2)n2ncc(Br)c2n1

InChI Key: InChIKey=CEWHMIZIYKEIJM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50223570   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50223570 (3-bromo-5-(2-fluorophenyl)-N-phenylpyrazolo[1,5-a]...) Show SMILES Fc1ccccc1-c1cc(Nc2ccccc2)n2ncc(Br)c2n1 Show InChI InChI=1S/C18H12BrFN4/c19-14-11-21-24-17(22-12-6-2-1-3-7-12)10-16(23-18(14)24)13-8-4-5-9-15(13)20/h1-11,22H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.33E+4	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of human GSK3beta				Bioorg Med Chem Lett 17: 6220-3 (2007) Article DOI: 10.1016/j.bmcl.2007.09.017 BindingDB Entry DOI: 10.7270/Q27M07ND
					More data for this Ligand-Target Pair