BDBM50223581 3-bromo-N-(pyridin-3-ylmethyl)-5-(thiophen-2-yl)pyrazolo[1,5-a]pyrimidin-7-amine::CHEMBL404208

SMILES: Brc1cnn2c(NCc3cccnc3)cc(nc12)-c1cccs1

InChI Key: InChIKey=JQSIFAJCGCUSRC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50223581   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50223581 (3-bromo-N-(pyridin-3-ylmethyl)-5-(thiophen-2-yl)py...) Show SMILES Brc1cnn2c(NCc3cccnc3)cc(nc12)-c1cccs1 Show InChI InChI=1S/C16H12BrN5S/c17-12-10-20-22-15(19-9-11-3-1-5-18-8-11)7-13(21-16(12)22)14-4-2-6-23-14/h1-8,10,19H,9H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of human GSK3beta				Bioorg Med Chem Lett 17: 6220-3 (2007) Article DOI: 10.1016/j.bmcl.2007.09.017 BindingDB Entry DOI: 10.7270/Q27M07ND
					More data for this Ligand-Target Pair