BDBM50223587 3-bromo-5-(2-chlorophenyl)-N-((pyridin-3-yloxy)methyl)pyrazolo[1,5-a]pyrimidin-7-amine::CHEMBL398621

SMILES: Clc1ccccc1-c1cc(NCOc2cccnc2)n2ncc(Br)c2n1

InChI Key: InChIKey=QGUUCHXMALEGPB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50223587   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50223587 (3-bromo-5-(2-chlorophenyl)-N-((pyridin-3-yloxy)met...) Show SMILES Clc1ccccc1-c1cc(NCOc2cccnc2)n2ncc(Br)c2n1 Show InChI InChI=1S/C18H13BrClN5O/c19-14-10-23-25-17(22-11-26-12-4-3-7-21-9-12)8-16(24-18(14)25)13-5-1-2-6-15(13)20/h1-10,22H,11H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of human GSK3beta				Bioorg Med Chem Lett 17: 6220-3 (2007) Article DOI: 10.1016/j.bmcl.2007.09.017 BindingDB Entry DOI: 10.7270/Q27M07ND
					More data for this Ligand-Target Pair