BDBM50223792 1-(((2R,3S,5S)-2-(hydroxymethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-tetrahydrofuran-3-yl)methyl)-3-(((2S,3R,5R)-2-(hydroxymethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-tetrahydrofuran-3-yl)methyl)urea::CHEMBL237839

SMILES: Cc1cn([C@H]2C[C@H](CNC(=O)NC[C@@H]3C[C@H](O[C@H]3CO)n3cc(C)c(=O)[nH]c3=O)[C@@H](CO)O2)c(=O)[nH]c1=O

InChI Key: InChIKey=ZPWVURMEGZTAOU-COYYTBTLSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50223792   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thymidylate kinase (Mycobacterium tuberculosis)	BDBM50223792 (1-(((2R,3S,5S)-2-(hydroxymethyl)-5-(5-methyl-2,4-d...) Show SMILES Cc1cn([C@H]2C[C@H](CNC(=O)NC[C@@H]3C[C@H](O[C@H]3CO)n3cc(C)c(=O)[nH]c3=O)[C@@H](CO)O2)c(=O)[nH]c1=O Show InChI InChI=1S/C23H32N6O9/c1-11-7-28(22(35)26-19(11)32)17-3-13(15(9-30)37-17)5-24-21(34)25-6-14-4-18(38-16(14)10-31)29-8-12(2)20(33)27-23(29)36/h7-8,13-18,30-31H,3-6,9-10H2,1-2H3,(H2,24,25,34)(H,26,32,35)(H,27,33,36)/t13-,14+,15-,16+,17-,18+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.70E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Gent Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis TMPK expressed in Escherichia coli by spectrophotometric assay				J Med Chem 50: 5281-92 (2007) Article DOI: 10.1021/jm0706158 BindingDB Entry DOI: 10.7270/Q2QJ7H1Z
					More data for this Ligand-Target Pair