BindingDB logo
myBDB logout

null

SMILES: COc1ccc(Sc2ccc3N=C4NCCN4Cc3c2)cc1

InChI Key: InChIKey=RIZFVUNDZZLBEV-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50223841   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prostacyclin receptor


(Homo sapiens (Human))		BDBM50223841
PNG
(CHEMBL9166)
Show SMILES COc1ccc(Sc2ccc3N=C4NCCN4Cc3c2)cc1 |t:11|
Show InChI InChI=1S/C17H17N3OS/c1-21-13-2-4-14(5-3-13)22-15-6-7-16-12(10-15)11-20-9-8-18-17(20)19-16/h2-7,10H,8-9,11H2,1H3,(H,18,19)
NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
<1.00E+4n/an/an/an/an/an/an/an/a



Roche Palo Alto

Curated by ChEMBL


Assay Description
Binding affinity towards prostacyclin receptor on rat NG-108-15 neuroblastoma cells, using [3H]iloprost as a radioligand

Bioorg Med Chem Lett 14: 1053-6 (2004)


BindingDB Entry DOI: 10.7270/Q2M90BVN
More data for this
Ligand-Target Pair