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SMILES: [H][C@@]12C[C@@H](C[C@]1([H])C[C@@](C2)(C#N)c1ccc(OC)c(OC2Cc3ccccc3C2)c1)C(O)=O

InChI Key: InChIKey=MFMSLIOHRZHOEC-NZKCOSSBSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50223945   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D


(Homo sapiens (Human))		BDBM50223945
PNG
(CHEMBL264369)
Show SMILES [H][C@@]12C[C@@H](C[C@]1([H])C[C@@](C2)(C#N)c1ccc(OC)c(OC2Cc3ccccc3C2)c1)C(O)=O
Show InChI InChI=1S/C26H27NO4/c1-30-23-7-6-21(12-24(23)31-22-10-16-4-2-3-5-17(16)11-22)26(15-27)13-19-8-18(25(28)29)9-20(19)14-26/h2-7,12,18-20,22H,8-11,13-14H2,1H3,(H,28,29)/t18-,19-,20+,26-
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 1.30n/an/an/an/an/an/a



Minase Research Institute

Curated by ChEMBL


Assay Description
Inhibition of PDE4 from U937 monocytic cells

Bioorg Med Chem Lett 14: 1323-7 (2004)


BindingDB Entry DOI: 10.7270/Q2BR8VCM
More data for this
Ligand-Target Pair