BDBM50224027 (S)-6-(4-(2-(3-(3,3-dibenzyl-2-oxoindolin-4-yloxy)-2-hydroxypropylamino)-2-methylpropyl)phenoxy)nicotinamide::CHEMBL250579

SMILES: CC(C)(Cc1ccc(Oc2ccc(cn2)C(N)=O)cc1)NC[C@H](O)COc1cccc2NC(=O)C(Cc3ccccc3)(Cc3ccccc3)c12

InChI Key: InChIKey=BGHYFJPSEDCVLZ-YTTGMZPUSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50224027   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-2 adrenergic receptor (Homo sapiens (Human))	BDBM50224027 ((S)-6-(4-(2-(3-(3,3-dibenzyl-2-oxoindolin-4-yloxy)...) Show SMILES CC(C)(Cc1ccc(Oc2ccc(cn2)C(N)=O)cc1)NC[C@H](O)COc1cccc2NC(=O)C(Cc3ccccc3)(Cc3ccccc3)c12 Show InChI InChI=1S/C41H42N4O5/c1-40(2,22-30-16-19-33(20-17-30)50-36-21-18-31(25-43-36)38(42)47)44-26-32(46)27-49-35-15-9-14-34-37(35)41(39(48)45-34,23-28-10-5-3-6-11-28)24-29-12-7-4-8-13-29/h3-21,25,32,44,46H,22-24,26-27H2,1-2H3,(H2,42,47)(H,45,48)/t32-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Agonist activity at human beta-2 adrenergic receptor expressed in CHO cells assessed as cAMP level				Bioorg Med Chem Lett 17: 6270-3 (2007) Article DOI: 10.1016/j.bmcl.2007.09.011 BindingDB Entry DOI: 10.7270/Q22V2FV6
					More data for this Ligand-Target Pair
Beta-1 adrenergic receptor (Homo sapiens (Human))	BDBM50224027 ((S)-6-(4-(2-(3-(3,3-dibenzyl-2-oxoindolin-4-yloxy)...) Show SMILES CC(C)(Cc1ccc(Oc2ccc(cn2)C(N)=O)cc1)NC[C@H](O)COc1cccc2NC(=O)C(Cc3ccccc3)(Cc3ccccc3)c12 Show InChI InChI=1S/C41H42N4O5/c1-40(2,22-30-16-19-33(20-17-30)50-36-21-18-31(25-43-36)38(42)47)44-26-32(46)27-49-35-15-9-14-34-37(35)41(39(48)45-34,23-28-10-5-3-6-11-28)24-29-12-7-4-8-13-29/h3-21,25,32,44,46H,22-24,26-27H2,1-2H3,(H2,42,47)(H,45,48)/t32-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Agonist activity at human beta-1 adrenergic receptor expressed in CHO cells assessed as cAMP level				Bioorg Med Chem Lett 17: 6270-3 (2007) Article DOI: 10.1016/j.bmcl.2007.09.011 BindingDB Entry DOI: 10.7270/Q22V2FV6
					More data for this Ligand-Target Pair
Beta-3 adrenergic receptor (Homo sapiens (Human))	BDBM50224027 ((S)-6-(4-(2-(3-(3,3-dibenzyl-2-oxoindolin-4-yloxy)...) Show SMILES CC(C)(Cc1ccc(Oc2ccc(cn2)C(N)=O)cc1)NC[C@H](O)COc1cccc2NC(=O)C(Cc3ccccc3)(Cc3ccccc3)c12 Show InChI InChI=1S/C41H42N4O5/c1-40(2,22-30-16-19-33(20-17-30)50-36-21-18-31(25-43-36)38(42)47)44-26-32(46)27-49-35-15-9-14-34-37(35)41(39(48)45-34,23-28-10-5-3-6-11-28)24-29-12-7-4-8-13-29/h3-21,25,32,44,46H,22-24,26-27H2,1-2H3,(H2,42,47)(H,45,48)/t32-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	268	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Agonist activity at human beta-3 adrenergic receptor expressed in CHO cells assessed as cAMP level				Bioorg Med Chem Lett 17: 6270-3 (2007) Article DOI: 10.1016/j.bmcl.2007.09.011 BindingDB Entry DOI: 10.7270/Q22V2FV6
					More data for this Ligand-Target Pair