BDBM50224032 6-[4-(2-{[(2S)-2-hydroxy-3-{2'-oxo-1',2'-dihydrospiro[cyclopentane-1,3'-indole]-4'-yloxy}propyl]amino}-2-methylpropyl)phenoxy]pyridine-3-carboxamide::CHEMBL430392

SMILES: CC(C)(Cc1ccc(Oc2ccc(cn2)C(N)=O)cc1)NC[C@H](O)COc1cccc2NC(=O)C3(CCCC3)c12

InChI Key: InChIKey=QXPQGOYPJBKDKD-QFIPXVFZSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50224032   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-2 adrenergic receptor (Homo sapiens (Human))	BDBM50224032 (6-[4-(2-{[(2S)-2-hydroxy-3-{2'-oxo-1',2'-dihydrosp...) Show SMILES CC(C)(Cc1ccc(Oc2ccc(cn2)C(N)=O)cc1)NC[C@H](O)COc1cccc2NC(=O)C3(CCCC3)c12 Show InChI InChI=1S/C31H36N4O5/c1-30(2,16-20-8-11-23(12-9-20)40-26-13-10-21(17-33-26)28(32)37)34-18-22(36)19-39-25-7-5-6-24-27(25)31(29(38)35-24)14-3-4-15-31/h5-13,17,22,34,36H,3-4,14-16,18-19H2,1-2H3,(H2,32,37)(H,35,38)/t22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Agonist activity at human beta-2 adrenergic receptor expressed in CHO cells assessed as cAMP level				Bioorg Med Chem Lett 17: 6270-3 (2007) Article DOI: 10.1016/j.bmcl.2007.09.011 BindingDB Entry DOI: 10.7270/Q22V2FV6
					More data for this Ligand-Target Pair
Beta-1 adrenergic receptor (Homo sapiens (Human))	BDBM50224032 (6-[4-(2-{[(2S)-2-hydroxy-3-{2'-oxo-1',2'-dihydrosp...) Show SMILES CC(C)(Cc1ccc(Oc2ccc(cn2)C(N)=O)cc1)NC[C@H](O)COc1cccc2NC(=O)C3(CCCC3)c12 Show InChI InChI=1S/C31H36N4O5/c1-30(2,16-20-8-11-23(12-9-20)40-26-13-10-21(17-33-26)28(32)37)34-18-22(36)19-39-25-7-5-6-24-27(25)31(29(38)35-24)14-3-4-15-31/h5-13,17,22,34,36H,3-4,14-16,18-19H2,1-2H3,(H2,32,37)(H,35,38)/t22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Agonist activity at human beta-1 adrenergic receptor expressed in CHO cells assessed as cAMP level				Bioorg Med Chem Lett 17: 6270-3 (2007) Article DOI: 10.1016/j.bmcl.2007.09.011 BindingDB Entry DOI: 10.7270/Q22V2FV6
					More data for this Ligand-Target Pair
Beta-3 adrenergic receptor (Homo sapiens (Human))	BDBM50224032 (6-[4-(2-{[(2S)-2-hydroxy-3-{2'-oxo-1',2'-dihydrosp...) Show SMILES CC(C)(Cc1ccc(Oc2ccc(cn2)C(N)=O)cc1)NC[C@H](O)COc1cccc2NC(=O)C3(CCCC3)c12 Show InChI InChI=1S/C31H36N4O5/c1-30(2,16-20-8-11-23(12-9-20)40-26-13-10-21(17-33-26)28(32)37)34-18-22(36)19-39-25-7-5-6-24-27(25)31(29(38)35-24)14-3-4-15-31/h5-13,17,22,34,36H,3-4,14-16,18-19H2,1-2H3,(H2,32,37)(H,35,38)/t22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	11	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Agonist activity at human beta-3 adrenergic receptor expressed in CHO cells assessed as cAMP level				Bioorg Med Chem Lett 17: 6270-3 (2007) Article DOI: 10.1016/j.bmcl.2007.09.011 BindingDB Entry DOI: 10.7270/Q22V2FV6
					More data for this Ligand-Target Pair