BDBM50224416 4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-yl)-N-[(3R)-2-oxo-6-pyridin-2-ylazepan-3-yl]piperidine-1-carboxamide::CHEMBL398779

SMILES: O=C(N[C@@H]1CCC(CNC1=O)c1ccccn1)N1CCC(CC1)n1c2cccnc2[nH]c1=O

InChI Key: InChIKey=DFQNEGLXPXMOFS-KPMSDPLLSA-N

Data: 1 KI

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50224416   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
CGRP type 1 receptor (Homo sapiens (Human))	BDBM50224416 (4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-yl...) Show SMILES O=C(N[C@@H]1CCC(CNC1=O)c1ccccn1)N1CCC(CC1)n1c2cccnc2[nH]c1=O Show InChI InChI=1S/C23H27N7O3/c31-21-18(7-6-15(14-26-21)17-4-1-2-10-24-17)27-22(32)29-12-8-16(9-13-29)30-19-5-3-11-25-20(19)28-23(30)33/h1-5,10-11,15-16,18H,6-9,12-14H2,(H,26,31)(H,27,32)(H,25,28,33)/t15?,18-/m1/s1	PDB GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]CGPR from human CL receptor expressed in HEK293 cells				J Med Chem 50: 5564-7 (2007) Article DOI: 10.1021/jm070668p BindingDB Entry DOI: 10.7270/Q28C9W02
					More data for this Ligand-Target Pair