BDBM50224439 CHEMBL240903::N-[(3R)-6-(4-methylphenyl)-2-oxoazepan-3-yl]-4-(2-oxo-2,3-dihydro-1Himidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide

SMILES: Cc1ccc(cc1)C1CC[C@@H](NC(=O)N2CCC(CC2)n2c3cccnc3[nH]c2=O)C(=O)NC1

InChI Key: InChIKey=PIQUKGNTPLBCHF-ROPPNANJSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50224439   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcitonin gene-related peptide type 1 receptor (Homo sapiens (Human))	BDBM50224439 (CHEMBL240903 | N-[(3R)-6-(4-methylphenyl)-2-oxoaze...) Show SMILES Cc1ccc(cc1)C1CC[C@@H](NC(=O)N2CCC(CC2)n2c3cccnc3[nH]c2=O)C(=O)NC1 Show InChI InChI=1S/C25H30N6O3/c1-16-4-6-17(7-5-16)18-8-9-20(23(32)27-15-18)28-24(33)30-13-10-19(11-14-30)31-21-3-2-12-26-22(21)29-25(31)34/h2-7,12,18-20H,8-11,13-15H2,1H3,(H,27,32)(H,28,33)(H,26,29,34)/t18?,20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]CGPR from human CL receptor expressed in HEK293 cells				J Med Chem 50: 5564-7 (2007) Article DOI: 10.1021/jm070668p BindingDB Entry DOI: 10.7270/Q28C9W02
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