BDBM50224705 1-(3-aminobenzo[d]isoxazol-5-yl)-5-(5-(2-((dimethylamino)methyl)-1H-imidazol-1-yl)indoline-1-carbonyl)-1H-pyrazole-3-carboxamide::CHEMBL251158

SMILES: CN(C)Cc1nccn1-c1ccc2N(CCc2c1)C(=O)c1cc(nn1-c1ccc2onc(N)c2c1)C(N)=O

InChI Key: InChIKey=RZGTUPGVGMDLEU-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50224705   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50224705 (1-(3-aminobenzo[d]isoxazol-5-yl)-5-(5-(2-((dimethy...) Show SMILES CN(C)Cc1nccn1-c1ccc2N(CCc2c1)C(=O)c1cc(nn1-c1ccc2onc(N)c2c1)C(N)=O Show InChI InChI=1S/C26H25N9O3/c1-32(2)14-23-29-8-10-33(23)16-3-5-20-15(11-16)7-9-34(20)26(37)21-13-19(25(28)36)30-35(21)17-4-6-22-18(12-17)24(27)31-38-22/h3-6,8,10-13H,7,9,14H2,1-2H3,(H2,27,31)(H2,28,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human factor 10a				Bioorg Med Chem Lett 17: 6481-8 (2007) Article DOI: 10.1016/j.bmcl.2007.09.091 BindingDB Entry DOI: 10.7270/Q2GX4B9Z
					More data for this Ligand-Target Pair