BDBM50224736 2-(4-(pyrrolidin-1-yl)phenyl)-3H-imidazo[4,5-b]pyridine::CHEMBL236938

SMILES: C1CCN(C1)c1ccc(cc1)-c1nc2ncccc2[nH]1

InChI Key: InChIKey=PXDVYKILWWGVFG-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50224736   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase A (Homo sapiens (Human))	BDBM50224736 (2-(4-(pyrrolidin-1-yl)phenyl)-3H-imidazo[4,5-b]pyr...) Show SMILES C1CCN(C1)c1ccc(cc1)-c1nc2ncccc2[nH]1 Show InChI InChI=1S/C16H16N4/c1-2-11-20(10-1)13-7-5-12(6-8-13)15-18-14-4-3-9-17-16(14)19-15/h3-9H,1-2,10-11H2,(H,17,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jinan University Curated by ChEMBL					Assay Description Inhibition of Aurora A				Eur J Med Chem 46: 77-94 (2010) Article DOI: 10.1016/j.ejmech.2010.10.017 BindingDB Entry DOI: 10.7270/Q25X296N
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM50224736 (2-(4-(pyrrolidin-1-yl)phenyl)-3H-imidazo[4,5-b]pyr...) Show SMILES C1CCN(C1)c1ccc(cc1)-c1nc2ncccc2[nH]1 Show InChI InChI=1S/C16H16N4/c1-2-11-20(10-1)13-7-5-12(6-8-13)15-18-14-4-3-9-17-16(14)19-15/h3-9H,1-2,10-11H2,(H,17,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of aurora A kinase				Bioorg Med Chem Lett 17: 6567-71 (2007) Article DOI: 10.1016/j.bmcl.2007.09.076 BindingDB Entry DOI: 10.7270/Q27D2TVT
					More data for this Ligand-Target Pair