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SMILES: CN(C)c1ccc(cc1)-c1nc2ncc(cc2[nH]1)C(F)(F)F

InChI Key: InChIKey=WGRWYEJKUYJJOR-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50224750   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Aurora kinase A


(Homo sapiens (Human))		BDBM50224750
PNG
(CHEMBL237144 | N,N-dimethyl-4-(6-(trifluoromethyl)...)
Show SMILES CN(C)c1ccc(cc1)-c1nc2ncc(cc2[nH]1)C(F)(F)F
Show InChI InChI=1S/C15H13F3N4/c1-22(2)11-5-3-9(4-6-11)13-20-12-7-10(15(16,17)18)8-19-14(12)21-13/h3-8H,1-2H3,(H,19,20,21)
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Article
PubMed
n/an/a 740n/an/an/an/an/an/a



Institute of Cancer Research

Curated by ChEMBL


Assay Description
Inhibition of aurora A kinase

Bioorg Med Chem Lett 17: 6567-71 (2007)


Article DOI: 10.1016/j.bmcl.2007.09.076
BindingDB Entry DOI: 10.7270/Q27D2TVT
More data for this
Ligand-Target Pair