BDBM50224853 5-(4-(4-(1H-benzo[d]imidazol-2-yl)phenoxy)phenoxy)-5-(2-ethoxyethyl)pyrimidine-2,4,6(1H,3H,5H)-trione::CHEMBL248543

SMILES: CCOCCC1(Oc2ccc(Oc3ccc(cc3)-c3nc4ccccc4[nH]3)cc2)C(=O)NC(=O)NC1=O

InChI Key: InChIKey=NJLYIWVYOOAOGD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50224853   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Collagenase 3 (Homo sapiens (Human))	BDBM50224853 (5-(4-(4-(1H-benzo[d]imidazol-2-yl)phenoxy)phenoxy)...) Show SMILES CCOCCC1(Oc2ccc(Oc3ccc(cc3)-c3nc4ccccc4[nH]3)cc2)C(=O)NC(=O)NC1=O Show InChI InChI=1S/C27H24N4O6/c1-2-35-16-15-27(24(32)30-26(34)31-25(27)33)37-20-13-11-19(12-14-20)36-18-9-7-17(8-10-18)23-28-21-5-3-4-6-22(21)29-23/h3-14H,2,15-16H2,1H3,(H,28,29)(H2,30,31,32,33,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.490	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research & Development Curated by ChEMBL					Assay Description Inhibition of MMP13				Bioorg Med Chem Lett 17: 6529-34 (2007) Article DOI: 10.1016/j.bmcl.2007.09.085 BindingDB Entry DOI: 10.7270/Q2ZW1KMR
					More data for this Ligand-Target Pair