BDBM50225002 2-(4-(2-(1-benzoylpiperidin-2-yl)ethoxy)phenyl)-1H-benzo[d]imidazole-5-carboxamide::CHEMBL250359

SMILES: NC(=O)c1ccc2nc([nH]c2c1)-c1ccc(OCCC2CCCCN2C(=O)c2ccccc2)cc1

InChI Key: InChIKey=HSAMVNWYINTDFJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50225002   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase CHK2 (Homo sapiens (Human))	BDBM50225002 (2-(4-(2-(1-benzoylpiperidin-2-yl)ethoxy)phenyl)-1H...) Show SMILES NC(=O)c1ccc2nc([nH]c2c1)-c1ccc(OCCC2CCCCN2C(=O)c2ccccc2)cc1 Show InChI InChI=1S/C28H28N4O3/c29-26(33)21-11-14-24-25(18-21)31-27(30-24)19-9-12-23(13-10-19)35-17-15-22-8-4-5-16-32(22)28(34)20-6-2-1-3-7-20/h1-3,6-7,9-14,18,22H,4-5,8,15-17H2,(H2,29,33)(H,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Inhibition of human recombinant Chk2				Bioorg Med Chem Lett 17: 6467-71 (2007) Article DOI: 10.1016/j.bmcl.2007.09.098 BindingDB Entry DOI: 10.7270/Q2KP81XB
					More data for this Ligand-Target Pair