BDBM50225055 (S)-1-((1S,5R)-2-aza-bicyclo[3.1.0]hexan-2-yl)-2-amino-2-(3,3,5,5-tetramethylcyclohexyl)ethanone::CHEMBL238232
SMILES: CC1(C)CC(CC(C)(C)C1)[C@H](N)C(=O)N1CC[C@@H]2C[C@H]12
InChI Key: InChIKey=RVJLKDVCEAWMIO-XBFCOCLRSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Dipeptidyl peptidase 4 (Homo sapiens (Human)) | BDBM50225055![]() ((S)-1-((1S,5R)-2-aza-bicyclo[3.1.0]hexan-2-yl)-2-a...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 152 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development Curated by ChEMBL | Assay Description Inhibition of human DPP4 | Bioorg Med Chem Lett 17: 6476-80 (2007) Article DOI: 10.1016/j.bmcl.2007.09.090 BindingDB Entry DOI: 10.7270/Q2B56JGM | |||||||||||
More data for this Ligand-Target Pair |