BDBM50225670 CHEMBL174346

SMILES: CS(O)(=O)=O.CCn1nc(c2CN(Cc3ccccc3)CCc12)-c1ccc(F)cc1

InChI Key: InChIKey=UNXPSKLHDBNCTL-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50225670   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50225670 (CHEMBL174346) Show SMILES CS(O)(=O)=O.CCn1nc(c2CN(Cc3ccccc3)CCc12)-c1ccc(F)cc1 Show InChI InChI=1S/C21H22FN3/c1-2-25-20-12-13-24(14-16-6-4-3-5-7-16)15-19(20)21(23-25)17-8-10-18(22)11-9-17/h3-11H,2,12-15H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.02E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to displace [3H]prazosin from postsynaptic alpha-1 adrenergic receptor of rat in vitro.				J Med Chem 28: 934-40 (1985) BindingDB Entry DOI: 10.7270/Q29C70NC
					More data for this Ligand-Target Pair