BDBM50225919 CHEMBL542874

SMILES: Cl.[H][C@@]12CCN(CCCCNC(C)=O)CC1c1cc(F)ccc1N2c1ccc(F)cc1

InChI Key: InChIKey=SCIISVFFAFWRKM-PZFASQSNSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50225919   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50225919 (CHEMBL542874) Show SMILES Cl.[H][C@@]12CCN(CCCCNC(C)=O)CC1c1cc(F)ccc1N2c1ccc(F)cc1 |r| Show InChI InChI=1S/C23H27F2N3O.ClH/c1-16(29)26-11-2-3-12-27-13-10-23-21(15-27)20-14-18(25)6-9-22(20)28(23)19-7-4-17(24)5-8-19;/h4-9,14,21,23H,2-3,10-13,15H2,1H3,(H,26,29);1H/t21?,23-;/m1./s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to displace [3H]spiroperidol from labeled Dopamine receptor of corpus striatum				J Med Chem 29: 2108-11 (1986) BindingDB Entry DOI: 10.7270/Q2RF5X74
					More data for this Ligand-Target Pair