BDBM50226515 CHEMBL416384

SMILES: CCCCc1nc(Cl)c(CO)n1Cc1ccc(cc1)C(O)=O

InChI Key: InChIKey=PPNBTJXOHVZWOB-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50226515   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin II receptor (RAT)	BDBM50226515 (CHEMBL416384) Show SMILES CCCCc1nc(Cl)c(CO)n1Cc1ccc(cc1)C(O)=O Show InChI InChI=1S/C16H19ClN2O3/c1-2-3-4-14-18-15(17)13(10-20)19(14)9-11-5-7-12(8-6-11)16(21)22/h5-8,20H,2-4,9-10H2,1H3,(H,21,22)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
E. I. du Pont de Nemours& Company, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration that gave 50 percent displacement of specific binding of [3H]AII (2 nM) to Angiotensin II receptor				J Med Chem 33: 1312-29 (1990) BindingDB Entry DOI: 10.7270/Q2TM7DCT
					More data for this Ligand-Target Pair
Angiotensin II receptor (AT-1) type-1 (RAT)	BDBM50226515 (CHEMBL416384) Show SMILES CCCCc1nc(Cl)c(CO)n1Cc1ccc(cc1)C(O)=O Show InChI InChI=1S/C16H19ClN2O3/c1-2-3-4-14-18-15(17)13(10-20)19(14)9-11-5-7-12(8-6-11)16(21)22/h5-8,20H,2-4,9-10H2,1H3,(H,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Inhibitory concentration that gives 50% displacement of specific binding at labeled angiotensin II type 1 receptor in rat adrenal cortical membranes.				J Med Chem 46: 716-26 (2003) Article DOI: 10.1021/jm021032v BindingDB Entry DOI: 10.7270/Q22B91RC
					More data for this Ligand-Target Pair
Angiotensin II receptor (AT-1) type-1 (RAT)	BDBM50226515 (CHEMBL416384) Show SMILES CCCCc1nc(Cl)c(CO)n1Cc1ccc(cc1)C(O)=O Show InChI InChI=1S/C16H19ClN2O3/c1-2-3-4-14-18-15(17)13(10-20)19(14)9-11-5-7-12(8-6-11)16(21)22/h5-8,20H,2-4,9-10H2,1H3,(H,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Inhibitory concentration that gives 50% displacement of specific binding at labeled angiotensin II type 1 receptor in rat adrenal cortical membranes.				J Med Chem 46: 716-26 (2003) Article DOI: 10.1021/jm021032v BindingDB Entry DOI: 10.7270/Q22B91RC
					More data for this Ligand-Target Pair