BDBM50226627 5,7,8,9,9a,10-hexahydro-7,10-methanopyrrolo[1,2-b][2,6]naphthyridin-3-amine::CHEMBL415265

SMILES: Nc1cc2CN3C4CCC3C(C4)c2cn1

InChI Key: InChIKey=KHHRTUOSBBRCOP-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50226627   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor Alpha-4/Beta-2 (Homo sapiens (Human))	BDBM50226627 (5,7,8,9,9a,10-hexahydro-7,10-methanopyrrolo[1,2-b]...) Show SMILES Nc1cc2CN3C4CCC3C(C4)c2cn1 |w:6.12,9.8,10.11,TLB:12:10:5:7.8,THB:4:5:7.8:10.11,TEB:8:9:6.11:4.3.12| Show InChI InChI=1S/C12H15N3/c13-12-3-7-6-15-8-1-2-11(15)9(4-8)10(7)5-14-12/h3,5,8-9,11H,1-2,4,6H2,(H2,13,14)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.24E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from alpha-4-beta-2 nAChR				J Med Chem 50: 6383-91 (2007) Article DOI: 10.1021/jm0704696 BindingDB Entry DOI: 10.7270/Q25H7HGG
					More data for this Ligand-Target Pair