BDBM50226790 CHEMBL353279

SMILES: CCCc1c(COc2ccc(cc2)C(C)c2nnn[nH]2)ccc(C(C)=O)c1O

InChI Key: InChIKey=GSZWFDBWUNJPJB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50226790   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cysteinyl leukotriene receptor (Homo sapiens (Human))	BDBM50226790 (CHEMBL353279) Show SMILES CCCc1c(COc2ccc(cc2)C(C)c2nnn[nH]2)ccc(C(C)=O)c1O Show InChI InChI=1S/C21H24N4O3/c1-4-5-19-16(8-11-18(14(3)26)20(19)27)12-28-17-9-6-15(7-10-17)13(2)21-22-24-25-23-21/h6-11,13,27H,4-5,12H2,1-3H3,(H,22,23,24,25)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of LTD4-induced contraction in guinea pig ileum				J Med Chem 30: 911-8 (1987) BindingDB Entry DOI: 10.7270/Q25X2B45
					More data for this Ligand-Target Pair