BDBM50226940 CHEMBL41456

SMILES: C(Cc1ccccc1)N1C(Cc2ccccc12)C1=NCCN1

InChI Key: InChIKey=MUVWVPJRKPGWFG-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50226940   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50226940 (CHEMBL41456) Show SMILES C(Cc1ccccc1)N1C(Cc2ccccc12)C1=NCCN1 |t:20| Show InChI InChI=1S/C19H21N3/c1-2-6-15(7-3-1)10-13-22-17-9-5-4-8-16(17)14-18(22)19-20-11-12-21-19/h1-9,18H,10-14H2,(H,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against alpha-2 adrenergic receptor was determined by the displacement of [3H]clonidine from rat brain cortical membranes				J Med Chem 30: 1555-62 (1987) BindingDB Entry DOI: 10.7270/Q2NC63FN
					More data for this Ligand-Target Pair