BDBM50227175 (R)-tetrahydro-2H-pyran-4-yl 1-(5-(2-(1H-indol-3-yl)ethyl)-4-(4-methoxybenzyl)-4H-1,2,4-triazol-3-yl)-2-(1H-indol-3-yl)ethylcarbamate::CHEMBL403426

SMILES: COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)OC2CCOCC2)cc1

InChI Key: InChIKey=CGTBJUIELRPANN-MGBGTMOVSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50227175   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ghrelin receptor (Homo sapiens (Human))	BDBM50227175 ((R)-tetrahydro-2H-pyran-4-yl 1-(5-(2-(1H-indol-3-y...) Show SMILES COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)OC2CCOCC2)cc1 Show InChI InChI=1S/C36H38N6O4/c1-44-27-13-10-24(11-14-27)23-42-34(15-12-25-21-37-31-8-4-2-6-29(25)31)40-41-35(42)33(39-36(43)46-28-16-18-45-19-17-28)20-26-22-38-32-9-5-3-7-30(26)32/h2-11,13-14,21-22,28,33,37-38H,12,15-20,23H2,1H3,(H,39,43)/t33-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	24	n/a	n/a	n/a	n/a
CNRS-Université Montpellier I Curated by ChEMBL					Assay Description Agonist activity at human GHSR1a receptor expressed in CHO cells assessed as intracellular calcium mobilization				Bioorg Med Chem Lett 18: 164-8 (2008) Article DOI: 10.1016/j.bmcl.2007.10.113 BindingDB Entry DOI: 10.7270/Q2HM586C
					More data for this Ligand-Target Pair
Ghrelin receptor (Homo sapiens (Human))	BDBM50227175 ((R)-tetrahydro-2H-pyran-4-yl 1-(5-(2-(1H-indol-3-y...) Show SMILES COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)OC2CCOCC2)cc1 Show InChI InChI=1S/C36H38N6O4/c1-44-27-13-10-24(11-14-27)23-42-34(15-12-25-21-37-31-8-4-2-6-29(25)31)40-41-35(42)33(39-36(43)46-28-16-18-45-19-17-28)20-26-22-38-32-9-5-3-7-30(26)32/h2-11,13-14,21-22,28,33,37-38H,12,15-20,23H2,1H3,(H,39,43)/t33-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
CNRS-Université Montpellier I Curated by ChEMBL					Assay Description Displacement of [125I]His9-ghrelin from human GHSR1a receptor expressed in LLC PK1 cells				Bioorg Med Chem Lett 18: 164-8 (2008) Article DOI: 10.1016/j.bmcl.2007.10.113 BindingDB Entry DOI: 10.7270/Q2HM586C
					More data for this Ligand-Target Pair