BDBM50227272 CHEMBL422131

SMILES: CC(=O)Nc1c(F)c(N2CCNCC2)c(F)c2n(cc(C(O)=O)c(=O)c12)C1CC1

InChI Key: InChIKey=AWDQYZYDTKHCHS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50227272   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA gyrase subunit A/B (Escherichia coli (strain K12))	BDBM50227272 (CHEMBL422131) Show SMILES CC(=O)Nc1c(F)c(N2CCNCC2)c(F)c2n(cc(C(O)=O)c(=O)c12)C1CC1 Show InChI InChI=1S/C19H20F2N4O4/c1-9(26)23-15-12-16(14(21)17(13(15)20)24-6-4-22-5-7-24)25(10-2-3-10)8-11(18(12)27)19(28)29/h8,10,22H,2-7H2,1H3,(H,23,26)(H,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>2.46E+5	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description 50% inhibitory concentration against DNA-gyrase				J Med Chem 31: 503-6 (1988) BindingDB Entry DOI: 10.7270/Q23B62BK
					More data for this Ligand-Target Pair