BDBM50227276 CHEMBL356984

SMILES: CCNCC1CCN(C1)c1c(F)c(NC(C)=O)c2c(c1F)n(cc(C(O)=O)c2=O)C1CC1

InChI Key: InChIKey=ILSWBOXSTIRMDL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50227276   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA gyrase subunit A/B (Escherichia coli (strain K12))	BDBM50227276 (CHEMBL356984) Show SMILES CCNCC1CCN(C1)c1c(F)c(NC(C)=O)c2c(c1F)n(cc(C(O)=O)c2=O)C1CC1 Show InChI InChI=1S/C22H26F2N4O4/c1-3-25-8-12-6-7-27(9-12)20-16(23)18(26-11(2)29)15-19(17(20)24)28(13-4-5-13)10-14(21(15)30)22(31)32/h10,12-13,25H,3-9H2,1-2H3,(H,26,29)(H,31,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>2.22E+5	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description 50% inhibitory concentration against DNA-gyrase				J Med Chem 31: 503-6 (1988) BindingDB Entry DOI: 10.7270/Q23B62BK
					More data for this Ligand-Target Pair