BDBM50227284 CHEMBL42299

SMILES: CN(C)c1c(F)c(N2CCN(C)CC2)c(F)c2n(cc(C(O)=O)c(=O)c12)C1CC1

InChI Key: InChIKey=LOTFWFMCODOSHI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50227284   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA Gyrase (Escherichia coli (strain K12))	BDBM50227284 (CHEMBL42299) Show SMILES CN(C)c1c(F)c(N2CCN(C)CC2)c(F)c2n(cc(C(O)=O)c(=O)c12)C1CC1 Show InChI InChI=1S/C20H24F2N4O3/c1-23(2)16-13-17(26(11-4-5-11)10-12(19(13)27)20(28)29)15(22)18(14(16)21)25-8-6-24(3)7-9-25/h10-11H,4-9H2,1-3H3,(H,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>4.92E+5	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description 50% inhibitory concentration against DNA-gyrase				J Med Chem 31: 503-6 (1988) BindingDB Entry DOI: 10.7270/Q23B62BK
					More data for this Ligand-Target Pair