BDBM50227393 (S)-N-(4-(4-fluorobenzylamino)-3,4-dioxo-1-phenylbutan-2-yl)-3-methyl-4-oxo-1,4-dihydroquinoline-2-carboxamide::CHEMBL253113

SMILES: Cc1c(O)c2ccccc2nc1C(=O)N[C@@H](Cc1ccccc1)C(=O)C(=O)NCc1ccc(F)cc1

InChI Key: InChIKey=BMUCAMYIELEPCV-QHCPKHFHSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50227393   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calpain1 (Homo sapiens (Human))	BDBM50227393 ((S)-N-(4-(4-fluorobenzylamino)-3,4-dioxo-1-phenylb...) Show SMILES Cc1c(O)c2ccccc2nc1C(=O)N[C@@H](Cc1ccccc1)C(=O)C(=O)NCc1ccc(F)cc1 Show InChI InChI=1S/C28H24FN3O4/c1-17-24(31-22-10-6-5-9-21(22)25(17)33)27(35)32-23(15-18-7-3-2-4-8-18)26(34)28(36)30-16-19-11-13-20(29)14-12-19/h2-14,23H,15-16H2,1H3,(H,30,36)(H,31,33)(H,32,35)/t23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.63E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kyung Hee University Curated by ChEMBL					Assay Description Inhibition of human mu-calpain				Bioorg Med Chem Lett 18: 205-9 (2008) Article DOI: 10.1016/j.bmcl.2007.10.097 BindingDB Entry DOI: 10.7270/Q2CV4HH3
					More data for this Ligand-Target Pair