BDBM50227402 (S)-N-(3,4-dioxo-1-phenyl-4-(pyridin-2-ylmethylamino)butan-2-yl)-3-methyl-4-oxo-1,4-dihydroquinoline-2-carboxamide::CHEMBL253314

SMILES: Cc1c(O)c2ccccc2nc1C(=O)N[C@@H](Cc1ccccc1)C(=O)C(=O)NCc1ccccn1

InChI Key: InChIKey=UJUIJEWKZRHLBS-QFIPXVFZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50227402   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calpain1 (Homo sapiens (Human))	BDBM50227402 ((S)-N-(3,4-dioxo-1-phenyl-4-(pyridin-2-ylmethylami...) Show SMILES Cc1c(O)c2ccccc2nc1C(=O)N[C@@H](Cc1ccccc1)C(=O)C(=O)NCc1ccccn1 Show InChI InChI=1S/C27H24N4O4/c1-17-23(30-21-13-6-5-12-20(21)24(17)32)26(34)31-22(15-18-9-3-2-4-10-18)25(33)27(35)29-16-19-11-7-8-14-28-19/h2-14,22H,15-16H2,1H3,(H,29,35)(H,30,32)(H,31,34)/t22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.72E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kyung Hee University Curated by ChEMBL					Assay Description Inhibition of human mu-calpain				Bioorg Med Chem Lett 18: 205-9 (2008) Article DOI: 10.1016/j.bmcl.2007.10.097 BindingDB Entry DOI: 10.7270/Q2CV4HH3
					More data for this Ligand-Target Pair