BDBM50227713 2-[4-(2-ethyl-biphenyl-4-yl)-3,6-dihydro-2H-pyridine-1-sulfonyl]-N-hydroxy-acetamide::CHEMBL398639

SMILES: CCc1cc(ccc1-c1ccccc1)C1=CCN(CC1)S(=O)(=O)CC(=O)NO

InChI Key: InChIKey=XRBRLEUPIULYDY-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50227713   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Stromelysin-1 (Homo sapiens (Human))	BDBM50227713 (2-[4-(2-ethyl-biphenyl-4-yl)-3,6-dihydro-2H-pyridi...) Show SMILES CCc1cc(ccc1-c1ccccc1)C1=CCN(CC1)S(=O)(=O)CC(=O)NO |t:16| Show InChI InChI=1S/C21H24N2O4S/c1-2-16-14-19(8-9-20(16)18-6-4-3-5-7-18)17-10-12-23(13-11-17)28(26,27)15-21(24)22-25/h3-10,14,25H,2,11-13,15H2,1H3,(H,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MMP3				Bioorg Med Chem Lett 17: 6750-3 (2008) Article DOI: 10.1016/j.bmcl.2007.10.042 BindingDB Entry DOI: 10.7270/Q20K289K
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50227713 (2-[4-(2-ethyl-biphenyl-4-yl)-3,6-dihydro-2H-pyridi...) Show SMILES CCc1cc(ccc1-c1ccccc1)C1=CCN(CC1)S(=O)(=O)CC(=O)NO |t:16| Show InChI InChI=1S/C21H24N2O4S/c1-2-16-14-19(8-9-20(16)18-6-4-3-5-7-18)17-10-12-23(13-11-17)28(26,27)15-21(24)22-25/h3-10,14,25H,2,11-13,15H2,1H3,(H,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.38E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MMP2				Bioorg Med Chem Lett 17: 6750-3 (2008) Article DOI: 10.1016/j.bmcl.2007.10.042 BindingDB Entry DOI: 10.7270/Q20K289K
					More data for this Ligand-Target Pair