BDBM50227744 3-(4-(3-((5-chloro-1,3-dimethyl-1H-indole-2-carboxamido)methyl)phenoxy)-2-methylphenyl)propanoic acid::CHEMBL238152

SMILES: Cc1c(C(=O)NCc2cccc(Oc3ccc(CCC(O)=O)c(C)c3)c2)n(C)c2ccc(Cl)cc12

InChI Key: InChIKey=SYVYIPUEDUCDLG-UHFFFAOYSA-N

Data: 3 IC50  3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50227744   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50227744 (3-(4-(3-((5-chloro-1,3-dimethyl-1H-indole-2-carbox...) Show SMILES Cc1c(C(=O)NCc2cccc(Oc3ccc(CCC(O)=O)c(C)c3)c2)n(C)c2ccc(Cl)cc12 Show InChI InChI=1S/C28H27ClN2O4/c1-17-13-23(10-7-20(17)8-12-26(32)33)35-22-6-4-5-19(14-22)16-30-28(34)27-18(2)24-15-21(29)9-11-25(24)31(27)3/h4-7,9-11,13-15H,8,12,16H2,1-3H3,(H,30,34)(H,32,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	44	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Agonist activity at human PPARgamma expressed in CV1 cells by receptor transactivation assay				Bioorg Med Chem Lett 17: 6744-9 (2008) Article DOI: 10.1016/j.bmcl.2007.10.047 BindingDB Entry DOI: 10.7270/Q2VT1RTW
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50227744 (3-(4-(3-((5-chloro-1,3-dimethyl-1H-indole-2-carbox...) Show SMILES Cc1c(C(=O)NCc2cccc(Oc3ccc(CCC(O)=O)c(C)c3)c2)n(C)c2ccc(Cl)cc12 Show InChI InChI=1S/C28H27ClN2O4/c1-17-13-23(10-7-20(17)8-12-26(32)33)35-22-6-4-5-19(14-22)16-30-28(34)27-18(2)24-15-21(29)9-11-25(24)31(27)3/h4-7,9-11,13-15H,8,12,16H2,1-3H3,(H,30,34)(H,32,33)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Agonist activity at human PPARdelta expressed in CV1 cells by receptor transactivation assay				Bioorg Med Chem Lett 17: 6744-9 (2008) Article DOI: 10.1016/j.bmcl.2007.10.047 BindingDB Entry DOI: 10.7270/Q2VT1RTW
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50227744 (3-(4-(3-((5-chloro-1,3-dimethyl-1H-indole-2-carbox...) Show SMILES Cc1c(C(=O)NCc2cccc(Oc3ccc(CCC(O)=O)c(C)c3)c2)n(C)c2ccc(Cl)cc12 Show InChI InChI=1S/C28H27ClN2O4/c1-17-13-23(10-7-20(17)8-12-26(32)33)35-22-6-4-5-19(14-22)16-30-28(34)27-18(2)24-15-21(29)9-11-25(24)31(27)3/h4-7,9-11,13-15H,8,12,16H2,1-3H3,(H,30,34)(H,32,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Displacement of [3H]-2-methyl-2-(4-{3-{propyl-(5-pyridin-2-yl-thiophene-2-sulfonyl)-amino}-propyl}-phenoxy)-propionic acid from human PPARgamma				Bioorg Med Chem Lett 17: 6744-9 (2008) Article DOI: 10.1016/j.bmcl.2007.10.047 BindingDB Entry DOI: 10.7270/Q2VT1RTW
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM50227744 (3-(4-(3-((5-chloro-1,3-dimethyl-1H-indole-2-carbox...) Show SMILES Cc1c(C(=O)NCc2cccc(Oc3ccc(CCC(O)=O)c(C)c3)c2)n(C)c2ccc(Cl)cc12 Show InChI InChI=1S/C28H27ClN2O4/c1-17-13-23(10-7-20(17)8-12-26(32)33)35-22-6-4-5-19(14-22)16-30-28(34)27-18(2)24-15-21(29)9-11-25(24)31(27)3/h4-7,9-11,13-15H,8,12,16H2,1-3H3,(H,30,34)(H,32,33)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.65E+3	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Agonist activity at human PPARalpha expressed in CV1 cells by receptor transactivation assay				Bioorg Med Chem Lett 17: 6744-9 (2008) Article DOI: 10.1016/j.bmcl.2007.10.047 BindingDB Entry DOI: 10.7270/Q2VT1RTW
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50227744 (3-(4-(3-((5-chloro-1,3-dimethyl-1H-indole-2-carbox...) Show SMILES Cc1c(C(=O)NCc2cccc(Oc3ccc(CCC(O)=O)c(C)c3)c2)n(C)c2ccc(Cl)cc12 Show InChI InChI=1S/C28H27ClN2O4/c1-17-13-23(10-7-20(17)8-12-26(32)33)35-22-6-4-5-19(14-22)16-30-28(34)27-18(2)24-15-21(29)9-11-25(24)31(27)3/h4-7,9-11,13-15H,8,12,16H2,1-3H3,(H,30,34)(H,32,33)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Displacement of [3H]-2-(4-{2-[3-(2,4-difluoro-phenyl)-1-heptyl-ureido]-ethyl}-phenoxy)-2-methyl-butyric acid from human PPARdelta				Bioorg Med Chem Lett 17: 6744-9 (2008) Article DOI: 10.1016/j.bmcl.2007.10.047 BindingDB Entry DOI: 10.7270/Q2VT1RTW
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM50227744 (3-(4-(3-((5-chloro-1,3-dimethyl-1H-indole-2-carbox...) Show SMILES Cc1c(C(=O)NCc2cccc(Oc3ccc(CCC(O)=O)c(C)c3)c2)n(C)c2ccc(Cl)cc12 Show InChI InChI=1S/C28H27ClN2O4/c1-17-13-23(10-7-20(17)8-12-26(32)33)35-22-6-4-5-19(14-22)16-30-28(34)27-18(2)24-15-21(29)9-11-25(24)31(27)3/h4-7,9-11,13-15H,8,12,16H2,1-3H3,(H,30,34)(H,32,33)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Displacement of [3H]-2-(4-{2-[3-(2,4-difluoro-phenyl)-1-heptyl-ureido]-ethyl}-phenoxy)-2-methyl-butyric acid from human PPARalpha				Bioorg Med Chem Lett 17: 6744-9 (2008) Article DOI: 10.1016/j.bmcl.2007.10.047 BindingDB Entry DOI: 10.7270/Q2VT1RTW
					More data for this Ligand-Target Pair